Reduced and oxidized glutathione concentrations in the lenses of riboflavin-deficient rats.
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Reduced and oxidized glutathione concentrations in the lenses of riboflavin-deficient rats.
The lens, in particular the lens epithelium, contains an uncommonly high concentration of reduced glutathione (GSH). It has been implicated to play a significant role in the maintenance of a reduced atmosphere in the lens. A diminution in the content of GSH has been observed during the formation of several forms of cataracts in experimental animals and in human subjects (1, 2). Glutathione redu...
متن کاملEndoplasmic reticulum : Reduced and oxidized glutathione
6 Division of Molecular and Systems Toxicology, Department of Pharmaceutical 7 Sciences, University of Basel, 4056 Basel, Switzerland 8 2 Swiss Center for Applied Human Toxicology, University of Basel, 4056 Basel, 9 Switzerland 10 3 INRES – Chemical Signalling, University of Bonn, 53113 Bonn, Germany 11 4 Department of Biology, University of Copenhagen, 2200 Copenhagen N, Denmark 12 5 D...
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15 صفحه اولEffect of orally administered reduced- and oxidized-glutathione against acetaminophen-induced liver injury in rats.
To investigate the effects of orally administered reduced-glutathione (GSH) and oxidized-glutathione (GSSG) on liver GSH repletion and liver injury, acetaminophen (AAP) highly loaded rats were used. Orally administered GSH, dependent on dosage, indicated a protective effect against AAP-induced hepatotoxicity. This effect was associated with a recovery of liver GSH levels. Orally administered GS...
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ژورنال
عنوان ژورنال: Journal of Nutritional Science and Vitaminology
سال: 1984
ISSN: 0301-4800,1881-7742
DOI: 10.3177/jnsv.30.401